Frequency of trisomy 15 and loss of the Y chromosome in adult leukemia.

  title={Frequency of trisomy 15 and loss of the Y chromosome in adult leukemia.},
  author={A. Smith and N. Watson and P. Sharma},
  journal={Cancer genetics and cytogenetics},
  volume={114 2},
  • A. Smith, N. Watson, P. Sharma
  • Published 1999
  • Biology, Medicine
  • Cancer genetics and cytogenetics
  • In the interpretation of the varied and complex cytogenetic counts obtained in analysis of bone marrow (BM) samples for leukemia, loss or gain of certain chromosomes may or may not be significant for prognosis. Loss of the Y chromosome in elderly males is a benign finding. Trisomy 15 is rare and may represent another age-related abnormality, particularly in males, together with -Y. We reviewed 3,242 routine referrals sent to our laboratory for BM cytogenetics, over a period of 34 months. We… CONTINUE READING
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