Frequency of specific coagulation inhibitors and antiphospholipid antibodies in Tunisian haemophiliacs.
@article{Kraiem2012FrequencyOS, title={Frequency of specific coagulation inhibitors and antiphospholipid antibodies in Tunisian haemophiliacs.}, author={I. Kraiem and S. Hadhri and H. el Omri and R. Sassi and W. Chaabani and S. Ennabli and H. Skouri}, journal={Annales de biologie clinique}, year={2012}, volume={70 6}, pages={ 659-65 } }
Production of factor VIII or factor IX inhibitors is a major complication limiting the efficiency of substitutive therapy in haemophiliacs. Moreover, viral infections, the second serious complication of replacement therapy, may be associated to the occurrence of antiphospholipid antibodies which paradoxically lead to thrombosis. We investigated the prevalence of coagulation inhibitors (factor VIII and factor IX inhibitors, antiphospholipid antibodies) in Tunisian haemophiliacs, and we assessed… CONTINUE READING
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References
SHOWING 1-10 OF 39 REFERENCES
Anti-factor VIII inhibitors and lupus anticoagulants in haemophilia A patients.
- Medicine
- Thrombosis and haemostasis
- 1997
- 30
Lupus anticoagulant, anticardiolipin antibodies, and human immunodeficiency virus in haemophilia.
- Medicine
- Journal of clinical pathology
- 1989
- 34
- PDF
Antiphospholipid antibodies in haemophilia patients with severe bleeding tendency: cause, consequence or a consequential cause?
- Medicine
- Haemophilia : the official journal of the World Federation of Hemophilia
- 2009
- 4
Lupus anticoagulants and their relationship with the inhibitors against coagulation factor VIII: considerations on the differentiation between the 2 circulating anticoagulants.
- Medicine
- Clinical chemistry
- 2005
- 35
- PDF
Incidence of factor VIII inhibitor development in hemophilia A patients treated with less pure plasma derived concentrates.
- Medicine
- Thrombosis and haemostasis
- 1994
- 68
Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A.
- Medicine
- Blood
- 2006
- 284
- PDF
Factor VIII haplotypes frequencies in Tunisian hemophiliacs A
- Biology, Medicine
- Diagnostic pathology
- 2011
- 7
The development of antiphospholipid antibodies in haemophilia is linked to infection with hepatitis C
- Medicine
- British journal of haematology
- 1994
- 54
Antiphospholipid antibodies, antiphospholipid syndrome and infections.
- Medicine
- Autoimmunity reviews
- 2008
- 152
Incidence of factor VIII inhibitors in severe haemophilia: the importance of patient age
- Medicine
- British journal of haematology
- 2001
- 167