Frequency of selective IgA deficiency among Brazilian blood donors and healthy pregnant women.

@article{CarneiroSampaio1989FrequencyOS,
  title={Frequency of selective IgA deficiency among Brazilian blood donors and healthy pregnant women.},
  author={Magda Maria Sales Carneiro-Sampaio and Solange Barros Carbonare and R B Rozentraub and Mogali de Araujo and M A Riberiro and M H Porto},
  journal={Allergologia et immunopathologia},
  year={1989},
  volume={17 4},
  pages={213-6}
}
Selective IgA deficiency (SIgAD) is the most common primary immunodeficiency, with frequencies ranging from 1:300 to 1:3,000 in populations surveyed in Europe and the US. In the present study we tested 11,576 clinically healthy persons (blood donors and pregnant women) for SIgAD (serum IgA less than 5 mg%). Serum samples were screened by double immunodiffusion with a sheep anti-human alpha-chain (minimal detection level of 30 mg%). Samples showing negative or doubtful reactions were submitted… CONTINUE READING