Frequency of measles virus-specific CD4+ and CD8+ T cells in subjects seronegative or highly seropositive for measles vaccine.

@article{Ovsyannikova2003FrequencyOM,
  title={Frequency of measles virus-specific CD4+ and CD8+ T cells in subjects seronegative or highly seropositive for measles vaccine.},
  author={Inna G. Ovsyannikova and Neelam Dhiman and Robert M. Jacobson and Robert A Vierkant and Gregory A. Poland},
  journal={Clinical and diagnostic laboratory immunology},
  year={2003},
  volume={10 3},
  pages={411-6}
}
The protective effect of measles immunization is due to humoral and cell-mediated immune responses. Little is known about cell-mediated immunity (CMI) to measles vaccine virus, the relative contribution of CD4(+) and CD8(+) T cells to variability in such immune responses, and the immunologic longevity of the CMI after measles vaccination in humans. Our study characterizes cellular immune response in subjects seronegative or highly seropositive for measles vaccine immunoglobulin G-specific… CONTINUE READING