Frequency of known gene rearrangements in endometrial stromal tumors.

@article{Chiang2011FrequencyOK,
  title={Frequency of known gene rearrangements in endometrial stromal tumors.},
  author={Sarah Chiang and Rola Ali and Nataliya Melnyk and Jessica N Mcalpine and David G. Huntsman and C. Blake Gilks and Cheng-Han Lee and Esther A Oliva},
  journal={The American journal of surgical pathology},
  year={2011},
  volume={35 9},
  pages={1364-72}
}
Translocations resulting in gene fusion are characteristic of endometrial stromal tumors (ESTs). Rearrangements of JAZF1, SUZ12, PHF1, and EPC1 have been reported in endometrial stromal nodules (ESNs), endometrial stromal sarcomas (ESSs), and rarely in undifferentiated endometrial sarcomas (UESs). Detection of JAZF1, SUZ12, EPC1, and PHF1 rearrangement by fluorescence in situ hybridization was performed on tissue microarrays consisting of 94 ESTs of classic and variant morphology (20 ESNs, 43… CONTINUE READING