Frequency of Infant Stroking Reported by Mothers Moderates the Effect of Prenatal Depression on Infant Behavioural and Physiological Outcomes

@inproceedings{Sharp2012FrequencyOI,
  title={Frequency of Infant Stroking Reported by Mothers Moderates the Effect of Prenatal Depression on Infant Behavioural and Physiological Outcomes},
  author={Helen Sharp and Andrew Pickles and Michael L Meaney and Kate L. A. Marshall and Florin Tibu and Jonathan Hill},
  booktitle={PloS one},
  year={2012}
}
Animal studies find that prenatal stress is associated with increased physiological and emotional reactivity later in life, mediated via fetal programming of the HPA axis through decreased glucocorticoid receptor (GR) gene expression. Post-natal behaviours, notably licking and grooming in rats, cause decreased behavioural indices of fear and reduced HPA axis reactivity mediated via increased GR gene expression. Post-natal maternal behaviours may therefore be expected to modify prenatal effects… CONTINUE READING
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