Frequency of HER2 expression of circulating tumour cells in patients with metastatic or recurrent gastrointestinal cancer

@inproceedings{Iwatsuki2013FrequencyOH,
  title={Frequency of HER2 expression of circulating tumour cells in patients with metastatic or recurrent gastrointestinal cancer},
  author={Masaaki Iwatsuki and Kyoichiro Toyoshima and Mika Watanabe and Naoko Hayashi and Takeshi Ishimoto and Ken Eto and Shiro Iwagami and Yuh Baba and Noriyuki Yoshida and Akimune Hayashi and Yoshikazu Ohta and Hideo Baba},
  booktitle={British Journal of Cancer},
  year={2013}
}
Background:The clinical significance of circulating tumour cell (CTC) detection in gastrointestinal (GI) cancer remains controversial and the molecular biological characteristics of CTCs are poorly understood.Methods:A total of 87 patients with metastatic or recurrent GI cancer were prospectively enrolled. Circulating tumour cells and their HER2 status were assessed using the CellSearch System.Results:Among the 62 CTC-positive cases, we found 22 discordant cases (35.5%). Among the HER2-negative… CONTINUE READING
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