Frequency of HER2 expression of circulating tumour cells in patients with metastatic or recurrent gastrointestinal cancer

@article{Iwatsuki2013FrequencyOH,
  title={Frequency of HER2 expression of circulating tumour cells in patients with metastatic or recurrent gastrointestinal cancer},
  author={M. Iwatsuki and K. Toyoshima and M. Watanabe and N. Hayashi and T. Ishimoto and Ken Eto and S. Iwagami and Y. Baba and N. Yoshida and A. Hayashi and Yoshikazu Ohta and H. Baba},
  journal={British Journal of Cancer},
  year={2013},
  volume={109},
  pages={2829 - 2832}
}
  • M. Iwatsuki, K. Toyoshima, +9 authors H. Baba
  • Published 2013
  • Medicine
  • British Journal of Cancer
  • Background:The clinical significance of circulating tumour cell (CTC) detection in gastrointestinal (GI) cancer remains controversial and the molecular biological characteristics of CTCs are poorly understood.Methods:A total of 87 patients with metastatic or recurrent GI cancer were prospectively enrolled. Circulating tumour cells and their HER2 status were assessed using the CellSearch System.Results:Among the 62 CTC-positive cases, we found 22 discordant cases (35.5%). Among the HER2-negative… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 17 REFERENCES
    HER-2 gene amplification can be acquired as breast cancer progresses.
    535
    HER2-Positive Circulating Tumor Cells in Breast Cancer
    164
    Detection and HER2 Expression of Circulating Tumor Cells: Prospective Monitoring in Breast Cancer Patients Treated in the Neoadjuvant GeparQuattro Trial
    402
    Circulating Tumor Cells in Colorectal Cancer: Past, Present, and Future Challenges
    85
    How many biopsy fragments will be necessary to assess HER2 status for gastric cancer?
    5
    Her2/neu testing in gastric cancer: evaluating the risk of sampling errors
    99