Frequency of BCR-ABL gene mutations in Polish patients with chronic myeloid leukemia treated with imatinib: a final report of the MAPTEST study.

@article{Lewandowski2009FrequencyOB,
  title={Frequency of BCR-ABL gene mutations in Polish patients with chronic myeloid leukemia treated with imatinib: a final report of the MAPTEST study.},
  author={Krzysztof Lewandowski and Krzysztof Warzocha and Andrzej Hellmann and Aleksander B. Skotnicki and Witold Prejzner and Kajetana Foryciarz and Tomasz Sacha and Michał Gniot and Mirosław Majewski and Iwona Solarska and Grażyna Nowak and Bartosz Wasąg and Mikołaj Kobelski and Cezary Ścibiorski and Marek Siemiątkowski and Maria Lewandowska and Mieczysław A. Komarnicki},
  journal={Polskie Archiwum Medycyny Wewnetrznej},
  year={2009},
  volume={119 12},
  pages={
          789-94
        }
}
  • Krzysztof Lewandowski, Krzysztof Warzocha, +14 authors Mieczysław A. Komarnicki
  • Published in
    Polskie Archiwum Medycyny…
    2009
  • Medicine
  • INTRODUCTION The presence of BCR-ABL oncogene mutations in patients with chronic myeloid leukemia (CML) may be responsible for the failure of tyrosine kinase inhibitor treatment. OBJECTIVES The aim of the study was to evaluate the frequency of BCR-ABL gene mutations in patients with CML (the MAPTEST study) treated with imatinib (IM). PATIENTS AND METHODS Direct sequencing analysis of BCR-ABL gene was performed in 92 patients treated with IM for more than 3 months. The mean time of IM… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 11 CITATIONS

    mplications of BCR-ABL 1 kinase domain-mediated resistance n chronic myeloid leukemia

    • imona Soverinia, Susan Branfordb, +6 authors Neil P. Shahj
    • 2013

    ABL kinase domain mutations in patients with chronic myeloid leukemia in Jordan.

    VIEW 1 EXCERPT
    CITES RESULTS

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 38 REFERENCES

    Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants.

    Recommendations for analysis of BCR‐ABL tyrosine kinase domain gene mutations in patients with chronic meylogenous leukemia: opinion accepted by the Polish Adult Leukemia Group

    • T Sacha, K Lewandowski, K Foryciarz
    • Acta Haematol Pol
    • 2008

    Several types of mutations of the Abl gene can be found in chronic myeloid leu‐ kemia patients resistant to ST157, and they can pre‐exist to the onset

    • C Roche‐Lestienne, V Soenen‐Cornu, N Grardel‐Duflos
    • logica
    • 2008