Frequency-dependent increase in cardiac Ca2+ current is due to reduced Ca2+ release by the sarcoplasmic reticulum.

@article{Delgado1999FrequencydependentII,
  title={Frequency-dependent increase in cardiac Ca2+ current is due to reduced Ca2+ release by the sarcoplasmic reticulum.},
  author={Carmen Delgado and Adriana Artiles and Ana M G{\'o}mez and Guy Vassort},
  journal={Journal of molecular and cellular cardiology},
  year={1999},
  volume={31 10},
  pages={1783-93}
}
"Ca(2+)-current facilitation" describes several features of increase in current amplitude often associated with a reduction in inactivation rate. The aim of this study was to investigate the mechanism of frequency-dependent increase in L-type Ca2+ current, I(Ca) taking advantage of recent knowledge on the control of Ca2+ current inactivation in cardiac… CONTINUE READING