Frequency and prognostic relevance of cyclin D1 dysregulation in multiple myeloma.

@article{Rasmussen2001FrequencyAP,
  title={Frequency and prognostic relevance of cyclin D1 dysregulation in multiple myeloma.},
  author={T Rasmussen and Lene Meldgaard Knudsen and Hans E. Johnsen},
  journal={European journal of haematology},
  year={2001},
  volume={67 5-6},
  pages={
          296-301
        }
}
OBJECTIVE Cyclin D1 dysregulation has been found with varying frequencies in multiple myeloma (MM) and has been suggested to be associated with a poor prognosis. The aim of this study was to investigate the frequency of cyclin D1 dysregulation in patients being treated for MM and to test whether cyclin D1 dysregulation is a prognostic factor for MM patients. METHODS To achieve the above aims we designed a highly sensitive and reproducible real-time reverse-transcription polymerase chain… CONTINUE READING

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