Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART

@inproceedings{Amu2014FrequencyAP,
  title={Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART},
  author={Sylvie Amu and Gitit Lavy-Shahaf and Alberto Cagigi and Bo Hejdeman and Silvia Nozza and L Lopalco and Ramit Mehr and F Chiodi},
  booktitle={Retrovirology},
  year={2014}
}
Aged individuals respond poorly to vaccination and have a higher risk of contracting infections in comparison to younger individuals; whether age impacts on the composition and function of B cell subpopulations relevant for immune responses is still controversial. It is also not known whether increased age during HIV-1 infection further synergizes with the virus to alter B cell subpopulations. In view of the increased number of HIV-1 infected patients living to high age as a result of anti… CONTINUE READING
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