Frequency and Pattern of Heteroplasmy in the Control Region of Human Mitochondrial DNA

Abstract

In this work, we present the results of the screening of human mitochondrial DNA (mtDNA) heteroplasmy in the control region of mtDNA from 210 unrelated Spanish individuals. Both hypervariable regions of mtDNA were amplified and sequenced in order to identify and quantify point and length heteroplasmy. Of the 210 individuals analyzed, 30% were fully… (More)
DOI: 10.1007/s00239-008-9138-9

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@article{Santos2008FrequencyAP, title={Frequency and Pattern of Heteroplasmy in the Control Region of Human Mitochondrial DNA}, author={Cristina Santos and Blanca Sierra and Luis Alvarez and Amanda Lu{\'i}ze Melo Tavares Ramos and Elisabet Fern{\'a}ndez and Ramon M Nogu{\'e}s and Mar{\'i}a Pilar Aluja}, journal={Journal of Molecular Evolution}, year={2008}, volume={67}, pages={191-200} }