Frequency-Specific Neural Signatures of Spontaneous Low-Frequency Resting State Fluctuations in Psychosis: Evidence From Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Consortium.

@article{Meda2015FrequencySpecificNS,
  title={Frequency-Specific Neural Signatures of Spontaneous Low-Frequency Resting State Fluctuations in Psychosis: Evidence From Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Consortium.},
  author={Shashwath A. Meda and Zheng Wang and Elena I Ivleva and Gaurav Poudyal and Matcheri S. Keshavan and Carol A. Tamminga and John A. Sweeney and Brett A. Clementz and David J. Schretlen and Vincent D. Calhoun and Su Lui and Eswar Damaraju and Godfrey D. Pearlson},
  journal={Schizophrenia bulletin},
  year={2015},
  volume={41 6},
  pages={1336-48}
}
BACKGROUND We quantified frequency-specific, absolute, and fractional amplitude of low-frequency fluctuations (ALFF/fALFF) across the schizophrenia (SZ)-psychotic bipolar disorder (PBP) psychosis spectrum using resting functional magnetic resonance imaging data from the large BSNIP family study. METHODS We assessed 242 healthy controls (HC), 547 probands (180 PBP, 220 SZ, and 147 schizoaffective disorder-SAD), and 410 of their first-degree relatives (134 PBPR, 150SZR, and 126 SADR). Following… CONTINUE READING
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