• Corpus ID: 46476449

Frequencies of VKORC1 -1639 G>A, CYP2C9*2 and CYP2C9*3 genetic variants in the Northern Indian population.

@article{Rathore2010FrequenciesOV,
  title={Frequencies of VKORC1 -1639 G>A, CYP2C9*2 and CYP2C9*3 genetic variants in the Northern Indian population.},
  author={Saurabh Singh Rathore and Surendra Kumar Agarwal and Shantanu Pande and Tulika Mittal and Balraj Mittal},
  journal={Bioscience trends},
  year={2010},
  volume={4 6},
  pages={
          333-7
        }
}
Dose requirements for oral anticoagulants in thromboembolic events are influenced by polymorphisms in VKORC1 and CYP2C9 genes. The Indian population comprises multiple ethnic groups but no data is available on allele frequencies of these genes for North Indians. The present study aimed at establishing the allele and genotype frequencies of VKORC1 -1639 G>A, CYP2C9*2 and CYP2C9*3 alleles in the North Indian population. One hundred and two healthy subjects from the Northern Indian region were… 

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