Frequencies of -308G/A (TNFA) and -509C/T (TGFB1) polymorphisms in sickle cell anemia patients from Brazil.

Abstract

Sickle cell anemia is an affection that causes chronic inflammation, with consequences for vaso-occlusion, oxidative stress and cytokine production. Genetic polymorphisms in markers involved in this process can modulate the inflammatory response, including polymorphisms -308G/A of TNFA (tumor necrosis factor alpha) and -509C/T of TGFB1 (transforming growth… (More)
DOI: 10.4238/2013.December.16.1

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@article{Torres2013FrequenciesO, title={Frequencies of -308G/A (TNFA) and -509C/T (TGFB1) polymorphisms in sickle cell anemia patients from Brazil.}, author={Lidiane de Souza Torres and {\'E}dis Belini J{\'u}nior and D. G. da Silva and Conceiç{\~a}o Lobo and M Anleles Ruiz and Cl{\'a}udia R. Bonini-Domingos}, journal={Genetics and molecular research : GMR}, year={2013}, volume={12 4}, pages={6762-6} }