Frequencies and types of exchange aberrations induced by X-rays and neutrons in Chinese hamster splenocytes detected by FISH using chromosome-specific DNA libraries.

@article{Grigorova1998FrequenciesAT,
  title={Frequencies and types of exchange aberrations induced by X-rays and neutrons in Chinese hamster splenocytes detected by FISH using chromosome-specific DNA libraries.},
  author={M. Grigorova and R. Brand and Y. Xiao and A. T. Natarajan},
  journal={International journal of radiation biology},
  year={1998},
  volume={74 3},
  pages={
          297-314
        }
}
  • M. Grigorova, R. Brand, +1 author A. T. Natarajan
  • Published 1998
  • Biology, Medicine
  • International journal of radiation biology
  • PURPOSE To estimate the frequencies of radiation- (low and high LET) induced chromosome aberrations in Chinese hamster splenocytes by two-colour fluorescence in situ hybridization using DNA painting probes specific for chromosomes 2, 3, 8, X and Y and to determine (1) the ratio of radiation-induced translocations and dicentrics; (2) the spectrum of exchange aberrations induced by X-rays and neutrons; and (3) the relative involvement of the different chromosomes in the formation of aberrations… CONTINUE READING
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