French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis.

Abstract

Segregation distortion has been reported to occur in a number of the trinucleotide repeat disorders. On the basis of a sperm typing study performed in patients of Japanese descent with Machado-Joseph disease (MJD), it was reported that disease alleles are preferentially transmitted during meiosis. We performed a sperm typing study of five MJD patients of… (More)

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Cite this paper

@article{Grewal1999FrenchMD, title={French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis.}, author={Raji Paul Grewal and G{\"{e}raldine Cancel and Esther P. Leeflang and Alexandra D{\"{u}rr and Mary Sara McPeek and D Draghinas and X Yao and Giovanni Stevanin and M O Alnot and Alexis Brice and Norman Arnheim}, journal={Human molecular genetics}, year={1999}, volume={8 9}, pages={1779-84} }