Freezing or wrapping: the role of particle size in the mechanism of nanoparticle-biomembrane interaction.

@article{Zhang2012FreezingOW,
  title={Freezing or wrapping: the role of particle size in the mechanism of nanoparticle-biomembrane interaction.},
  author={Shengwen Zhang and Andrew Nelson and Paul A. Beales},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2012},
  volume={28 35},
  pages={12831-7}
}
Understanding the interactions between nanoparticles (NPs) and biological matter is a high-priority research area because of the importance of elucidating the physical mechanisms underlying the interactions leading to NP potential toxicity as well as NP viability as therapeutic vectors in nanomedicine. Here, we use two model membrane systems, giant unilamellar vesicles (GUVs) and supported monolayers, to demonstrate the competition between adhesion and elastic energy at the nanobio interface… CONTINUE READING