Freeze fracture study of airway epithelium from patients with primary ciliary dyskinesia.

@article{Thai2002FreezeFS,
  title={Freeze fracture study of airway epithelium from patients with primary ciliary dyskinesia.},
  author={Channeary Thai and Todd M. Gambling and Johnny L. Carson},
  journal={Thorax},
  year={2002},
  volume={57 4},
  pages={363-5}
}
BACKGROUND The airway cilia of patients with primary ciliary dyskinesia (PCD) exhibit several anomalies when studied by transmission electron microscopy, but little is known about the ultrastructural organisation of ciliary membranes in these patients. Freeze fracture replication of airway epithelium from patients with PCD provides a means of achieving high resolution views of cell membrane structure. Ciliary necklaces are a specialised structural feature of ciliary membranes thought to serve… CONTINUE READING