Freeze-fracture of the normal and pathological megakaryocyte lineage in chronic megakaryocytic-granulocytic myelosis.

@article{Thiele1977FreezefractureOT,
  title={Freeze-fracture of the normal and pathological megakaryocyte lineage in chronic megakaryocytic-granulocytic myelosis.},
  author={Juergen Thiele and A C Ballard and Axel Georgii},
  journal={Virchows Archiv. B, Cell pathology},
  year={1977},
  volume={23 1},
  pages={33-51}
}
Freeze-fracture and thin sections were performed on human bone marrow of chronic megakaryocytic-granulocytic myelosis (CMGM) to study the three-dimensional fine structure and maturation of normal and atypical megakaryocytes and thrombocytes. In the many normally maturing megakaryocytes the development of the demarcation membrane system (DMS) was best… CONTINUE READING