Free radicals and endothelial dysfunction: potential positive effects of TNF-α inhibitors.

@article{Murdaca2013FreeRA,
  title={Free radicals and endothelial dysfunction: potential positive effects of TNF-α inhibitors.},
  author={Giuseppe Murdaca and Francesca Span{\`o} and Paola Cagnati and F Puppo},
  journal={Redox report : communications in free radical research},
  year={2013},
  volume={18 3},
  pages={
          95-9
        }
}
OBJECTIVES During the last decade many new biological immune modulators have entered the market as new therapeutic principles. Tumor necrosis factor (TNF)-α is a pro-inflammatory cytokine known to a have a key role in the pathogenic mechanisms of various immune-mediated or inflammatory diseases. However, TNF-α also plays a key role in endothelial dysfunction and, thus, in the development and progression of atherosclerosis. What, then, is the potential therapeutic role of TNF-α inhibitors… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

Infection risk associated with anti-TNF-α agents: a review.

  • Expert opinion on drug safety
  • 2015
VIEW 1 EXCERPT
CITES BACKGROUND

Similar Papers