Free radicals and disease.

  title={Free radicals and disease.},
  author={Jackob Moskovitz and Moon Bin Yim and P. Boon Chock},
  journal={Archives of biochemistry and biophysics},
  volume={397 2},
Free radicals and reactive oxygen species (ROS) have been associated with the etiology and/or progression of a number of diseases and in aging. Many of the proteins oxidatively modified by free radicals contain side-chain carbonyl derivatives, which can be used as markers for protein oxidation. The protein carbonyl content has been quantitated as a function of age for human cultured dermal fibroblasts, lens, and brain tissue. These data were analyzed using a simple autocatalytic model with the… CONTINUE READING

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