Free radicals, oxidative stress, and antioxidants in human health and disease

  title={Free radicals, oxidative stress, and antioxidants in human health and disease},
  author={O. Aruoma},
  journal={Journal of the American Oil Chemists' Society},
  pages={199 - 212}
  • O. Aruoma
  • Published 1998
  • Medicine, Chemistry
  • Journal of the American Oil Chemists' Society
  • Free radicals and other reactive oxygen species (ROS) are constantly formed in the human body. Free-radical mechanisms have been implicated in the pathology of several human diseases, including cancer, atherosclerosis, malaria, and rheumatoid arthritis and neurodegenerative diseases. For example, the superoxide radical (O2·−) and hydrogen peroxide (H2O2) are known to be generated in the brain and nervous system in vivo, and several areas of the human brain are rich in iron, which appears to be… CONTINUE READING
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