Free radicals, immunoglobulins and complement as mediators of inflammation.

@article{Roberts1988FreeRI,
  title={Free radicals, immunoglobulins and complement as mediators of inflammation.},
  author={Noel A. Roberts},
  journal={Bailliere's clinical rheumatology},
  year={1988},
  volume={2 1},
  pages={211-32}
}
There is evidence for both oxygen-centred free radicals and products of complement activation acting as mediators of inflammation. Evidence for the generation and reaction of free radicals at sites of inflammation can only be indirect and circumstantial due to their very transient nature. Evidence for complement activation in several inflammatory conditions, including rheumatoid arthritis is strong. These mediator classes individually possess a range of potential proinflammatory activities… CONTINUE READING
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