Free radical-scavenging activities of oligomeric proanthocyanidin from Rhodiola rosea L. and its antioxidant effects in vivo.

@article{Zhou2014FreeRA,
  title={Free radical-scavenging activities of oligomeric proanthocyanidin from Rhodiola rosea L. and its antioxidant effects in vivo.},
  author={Qian Zhou and Zhi-Ping Yin and Lei Ma and Wen Zhao and Hong-wei Hao and Huiling Li},
  journal={Natural product research},
  year={2014},
  volume={28 24},
  pages={2301-3}
}
This study aimed to determine the antioxidant activity of oligomeric proanthocyanidin from Rhodiola rosea L. (OPCRR). The free radical-scavenging activities exhibited by OPCRR, as determined by using 1,1-diphenyl-2-picrylhydrazyl, hydroxyl radical and superoxide anion (√[Formula: see text]) scavenging assays, were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
The free radical - scavenging activities exhibited by OPCRR , as determined by using 1,1-diphenyl-2-picrylhydrazyl , hydroxyl radical and superoxide anion ( √[Formula : see text ] ) scavenging assays , were greater than that of vitamin C. The effects of OPCRR on the antioxidant enzymes activity and lipid peroxide content in vivo were evaluated through three observation biomarkers , including superoxide dismutase ( SOD ) , glutathione peroxidase ( GSH - Px ) and malondialdehyde ( MDA ) in serum , heart , liver and brain tissues in mice .
All Topics