Free radical scavengers, catalase and superoxide dismutase provide protection from oxalate-associated injury to LLC-PK1 and MDCK cells.

@article{Thamilselvan2000FreeRS,
  title={Free radical scavengers, catalase and superoxide dismutase provide protection from oxalate-associated injury to LLC-PK1 and MDCK cells.},
  author={Sivagnanam Thamilselvan and Karen J. Byer and Raymond L. Hackett and Saeed R. Khan},
  journal={The Journal of urology},
  year={2000},
  volume={164 1},
  pages={224-9}
}
PURPOSE Current studies have provided evidence that exposure of renal epithelial cells to oxalate and calcium oxalate crystals induces lipid peroxidation and injures the cells. Since oxidant/antioxidant balance is likely to play a critical role, we determined the effect of antioxidant scavengers on production of free radicals and injury to LLC-PK1 and MDCK cells from exposure to oxalate (Ox) or Ox + calcium oxalate monohydrate (COM) crystals. MATERIALS AND METHODS LLC-PK1 and MDCK cells were… CONTINUE READING

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