Free radical induced respiratory muscle dysfunction

@article{Supinski1998FreeRI,
  title={Free radical induced respiratory muscle dysfunction},
  author={Gerald S. Supinski},
  journal={Molecular and Cellular Biochemistry},
  year={1998},
  volume={179},
  pages={99-110}
}
It is now recognized that respiratory muscle fatigue contributes to the development of respiratory failure in some patients with lung disease. This observation has prompted an examination into the mechanisms of development of muscle fatigue, with the understanding that an elucidation of these processes may lead to new therapeutic approaches to the treatment of these patients. A series of recent studies examining this issue have, moreover, discovered that oxygen-derived free radicals generated… CONTINUE READING