Free radical effects on lung metabolism.

  title={Free radical effects on lung metabolism.},
  author={Stephen Jenkinson},
  journal={Clinics in chest medicine},
  volume={10 1},
Exposure to hyperoxia or a number of different environmental toxins can result in free radical-mediated lung injury. Specific toxins and their activated breakdown products can produce free radicals and markedly change normal lung metabolism by reacting with cell membranes, intracellular proteins, and nucleic acids. Endogenous production of free radicals by polymorphonuclear leukocytes sequestered in the lung can also lead to lung damage. Numerous intracellular and extracellular free radical… CONTINUE READING