Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.

@article{SnchezReyes2014FreeFA,
  title={Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation.},
  author={Omar B. S{\'a}nchez-Reyes and Margarita Romero-{\'A}vila and Jean A. Castillo-Badillo and Yoshinori Takei and Akira Hirasawa and Gozoh Tsujimoto and Rafael Villalobos-Molina and Jes{\'u}s Adolfo Garc{\'i}a-S{\'a}inz},
  journal={European journal of pharmacology},
  year={2014},
  volume={723},
  pages={368-74}
}
GPR120, free fatty acid receptor 4, is a recently deorphanized G protein-coupled receptor that seems to play cardinal roles in the regulation of metabolism and in the pathophysiology of inflammatory and metabolic disorders. In the present work a GPR120-Venus fusion protein was expressed in HEK293 Flp-In T-REx cells and its function (increase in intracellular calcium) and phosphorylation were studied. It was observed that the fusion protein migrated in sodium dodecyl sulfate-polyacrylamide gels… CONTINUE READING
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Phosphorylation and internalization of short splicing variant of the omega 3 fatty acid sensor, GPR120

  • O. Sánchez-Reyes, J. Castillo-Badillo, +5 authors J. García-Sáinz
  • FASEB J. 27
  • 2013
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