Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes.

@article{Palmano1977FreeAL,
  title={Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes.},
  author={K. P. Palmano and Paul H. Whiting and John N. Hawthorne},
  journal={The Biochemical journal},
  year={1977},
  volume={167 1},
  pages={229-35}
}
Acute diabetes with ketosis was induced in rats by intraperitoneal streptozotocin and also a milder form of diabetes without ketosis by injecting less of the drug. The acutely diabetic rats were killed 72h after injection and the others after either 2 or 13 weeks. Free and lipid myo-inositol was then measured in various tissues and body fluids by g.l.c. of the trimethylsilyl ether. Serum inositol was increased in the acutely diabetic group, whereas liver inositol was decreased. Brain and kidney… CONTINUE READING
31 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Similar Papers

Loading similar papers…