Free HLA class I heavy chain-carrying monocytes--a potential role in the pathogenesis of spondyloarthropathies.

Abstract

OBJECTIVE A fully complexed HLA-B27 molecule consists of a heavy chain, a peptide, and beta2-microglobulin (beta2m). The heavy chain can also exist free of beta2m. It has been proposed from animal and in vitro experiments that the free heavy chain is responsible for disease. We wanted to determine the following for patients with ankylosing spondylitis (AS… (More)

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Cite this paper

@article{Tsai2002FreeHC, title={Free HLA class I heavy chain-carrying monocytes--a potential role in the pathogenesis of spondyloarthropathies.}, author={Wen Chan Tsai and Chung Jen Chen and Jeng Yen and Tsang Teng Ou and Jih Jin Tsai and Chiang - Shin Liu and Hong W. Liu}, journal={The Journal of rheumatology}, year={2002}, volume={29 5}, pages={966-72} }