Free D-aspartate in mammals.

  title={Free D-aspartate in mammals.},
  author={Takemitsu Furuchi and Hiroshi Homma},
  journal={Biological & pharmaceutical bulletin},
  volume={28 9},
D-Aspartate (D-Asp) is an endogenous amino acid present in nervous and endocrine tissues in mammals. A high concentration of D-Asp is observed in embryos, which disappears in nervous tissues after delivery, but increases temporarily in endocrine glands, particularly in the pituitary, pineal and adrenal glands at the specific stages. In the pineal gland, D-Asp that is apparently derived from other tissues suppresses melatonin secretion from parenchymal cells. Additionally, D-Asp levels increase… CONTINUE READING


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