Fraternal concordance of types of abnormal hepatocellular mitochondria in Wilson's disease.

@article{Sternlieb1992FraternalCO,
  title={Fraternal concordance of types of abnormal hepatocellular mitochondria in Wilson's disease.},
  author={Irmin Sternlieb},
  journal={Hepatology},
  year={1992},
  volume={16 3},
  pages={728-32}
}
Three distinct patterns of structural abnormalities of mitochondria, indicated as types I, II and III and associated with steatosis, were identified in the hepatocytes of 40 of 42 asymptomatic and 8 of 22 symptomatic patients with documented Wilson's disease before treatment. No correlation was seen between the type of mitochondrial abnormality and the patient's age, hepatic copper concentration, degree of hepatic steatosis or serum aminotransferase level. However, comparison of the types of… CONTINUE READING
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