Francisella tularensis enters macrophages via a novel process involving pseudopod loops.

@article{Clemens2005FrancisellaTE,
  title={Francisella tularensis enters macrophages via a novel process involving pseudopod loops.},
  author={Daniel L. Clemens and B Y Lee and Marcus A. Horwitz},
  journal={Infection and immunity},
  year={2005},
  volume={73 9},
  pages={5892-902}
}
Intracellular bacterial pathogens employ a variety of strategies to invade their eukaryotic host cells. From an ultrastructural standpoint, the processes that bacteria employ to invade their host cells include conventional phagocytosis, coiling phagocytosis, and ruffling/triggered macropinocytosis. In this paper, we describe a novel process by which Francisella tularensis, the agent of tularemia, enters host macrophages. F. tularensis is a remarkably infectious facultative intracellular… CONTINUE READING
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Tonat, and the Working Group on Civilian Biodefense

  • D. Dennis, T. Inglesby, +14 authors K.P.K. Russel
  • JAMA
  • 2001
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