Francisella novicida Forms In Vitro Biofilms Mediated by an Orphan Response Regulator

@article{DurhamColleran2009FrancisellaNF,
  title={Francisella novicida Forms In Vitro Biofilms Mediated by an Orphan Response Regulator},
  author={Meghan W. Durham-Colleran and Anne Brooks Verhoeven and Monique L. van Hoek},
  journal={Microbial Ecology},
  year={2009},
  volume={59},
  pages={457-465}
}
Francisella tularensis is associated with water and waterways and infects many species of animals, insects, and protists. The mechanism Francisella utilizes to persist in the environment and in tick vectors is currently unknown. We have demonstrated for the first time that Francisella novicida, a model organism of F. tularensis, forms a biofilm in vitro. Selected F. novicida transposon mutants were tested for their ability to form biofilm compared to the wildtype F. novicida strain. Mutation of… CONTINUE READING

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