Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia.

@article{Glodzik2011FraminghamCR,
  title={Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia.},
  author={Lidia Glodzik and Henry Rusinek and Miroslaw Brys and Wai Hon Tsui and Remigiusz Switalski and Lisa Mosconi and Rachel L Mistur and Elizabeth Pirraglia and Susan de Santi and Yi Li and Alexander Goldowsky and Mony J de Leon},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2011},
  volume={31 2},
  pages={671-9}
}
Vascular risk factors affect cerebral blood flow (CBF) and cerebral vascular reactivity, contributing to cognitive decline. Hippocampus is vulnerable to both Alzheimer's disease (AD) pathology and ischemia; nonetheless, the information about the impact of vascular risk on hippocampal perfusion is minimal. Cognitively, healthy elderly (NL=18, 69.9±6.7 years) and subjects with mild cognitive impairment (MCI=15, 74.9±8.1 years) were evaluated for the Framingham cardiovascular risk profile (FCRP… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 50 references

Carotid endarterectomy for asymptomatic carotid stenosis.

The New England journal of medicine • 1993
View 1 Excerpt
Highly Influenced

Brief Cognitive Rating Scale (BCRS).

Psychopharmacology bulletin • 1988
View 4 Excerpts
Highly Influenced

Hippocampal Blood Flow and Vascular Reactivity in Normal Aging

H Rusinek, L Glodzik, +4 authors MJ de Leon
Proceedings of the 18th scientific meeting ISMRM, • 2010
View 2 Excerpts

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