Frame disruptions in human mRNA transcripts, and their relationship with splicing and protein structures

Abstract

Efforts to gather genomic evidence for the processes of gene evolution are ongoing, and are closely coupled to improved gene annotation methods. Such annotation is complicated by the occurrence of disrupted mRNAs (dmRNAs), harbouring frameshifts and premature stop codons, which can be considered indicators of decay into pseudogenes. We have derived a… (More)
DOI: 10.1186/1471-2164-8-371

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Cite this paper

@article{Harrison2007FrameDI, title={Frame disruptions in human mRNA transcripts, and their relationship with splicing and protein structures}, author={P. Matthew Harrison and Zhan Yu}, journal={BMC Genomics}, year={2007}, volume={8}, pages={371 - 371} }