Fragmentation of slow wave sleep after onset of complete locked-in state.

  title={Fragmentation of slow wave sleep after onset of complete locked-in state.},
  author={Surjo R. Soekadar and Jan Born and Niels Birbaumer and Michael Bensch and Sebastian Halder and Ander Ramos Murguialday and Alireza Gharabaghi and Femke Nijboer and Bernhard Sch{\"o}lkopf and Suzanne Martens},
  journal={Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine},
  volume={9 9},
Locked-in syndrome (LIS) as a result of brainstem lesions or progressive neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), is a severe medical condition in which a person is fully conscious but unable to move or talk. LIS can transition into complete locked-in syndrome (CLIS) in which residual abilities to communicate through muscle twitches are entirely lost. It is unknown how CLIS affects circadian rhythm and sleep/wake patterns. Here we report a 39-year-old ALS… CONTINUE READING
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