Fragmentation dynamics of DNA sequence duplications

  title={Fragmentation dynamics of DNA sequence duplications},
  author={M. V. Koroteev and Johanna Miller},
Motivated by empirical observations of algebraic duplicated sequence length distributions in a broad range of natural genomes, we analytically formulate and solve a class of simple discrete dupli-cation/substitution models that generate steady-states sharing this property. Continuum equations are derived for arbitrary time-independent duplication length source distribution, a limit that we show can be mapped directly onto certain fragmentation models that have been intensively studied by… CONTINUE READING
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