Fragment-based drug discovery and its application to challenging drug targets.

Abstract

Fragment-based drug discovery (FBDD) is a technique for identifying low molecular weight chemical starting points for drug discovery. Since its inception 20 years ago, FBDD has grown in popularity to the point where it is now an established technique in industry and academia. The approach involves the biophysical screening of proteins against collections of… (More)
DOI: 10.1042/EBC20170029

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Cite this paper

@article{Price2017FragmentbasedDD, title={Fragment-based drug discovery and its application to challenging drug targets.}, author={Amanda Price and Steven Howard and Benjamin D Cons}, journal={Essays in biochemistry}, year={2017}, volume={61 5}, pages={475-484} }