Fracture risk with multiple myeloma: a population-based study.

@article{Melton2005FractureRW,
  title={Fracture risk with multiple myeloma: a population-based study.},
  author={Lee Joseph Melton and Robert A Kyle and Sara J. Achenbach and Ann L. Oberg and S Vincent Rajkumar},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2005},
  volume={20 3},
  pages={487-93}
}
UNLABELLED Pathologic fractures, especially of the axial skeleton, are extremely common in patients with multiple myeloma and cluster around the time of diagnosis. Osteoporotic fractures seem to be less of a problem in these patients. INTRODUCTION It is generally believed that fractures are common in patients with multiple myeloma as a result of lytic bone lesions, generalized bone loss, and/or elevated bone turnover from excessive cytokine production, but the actual risk of pathologic versus… CONTINUE READING
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