Fracture healing: mechanisms and interventions

  title={Fracture healing: mechanisms and interventions},
  author={Thomas A. Einhorn and Louis Charles Gerstenfeld},
  journal={Nature Reviews Rheumatology},
Fractures are the most common large-organ, traumatic injuries to humans. The repair of bone fractures is a postnatal regenerative process that recapitulates many of the ontological events of embryonic skeletal development. Although fracture repair usually restores the damaged skeletal organ to its pre-injury cellular composition, structure and biomechanical function, about 10% of fractures will not heal normally. This article reviews the developmental progression of fracture healing at the… CONTINUE READING
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