Fractionated radiosurgery for painful spinal metastases: DOSIS - a phase II trial

Abstract

One third of all cancer patients will develop bone metastases and the vertebral column is involved in approximately 70% of these patients. Conventional radiotherapy with of 1–10 fractions and total doses of 8-30 Gy is the current standard for painful vertebral metastases; however, the median pain response is short with 3–6 months and local tumor control is… (More)
DOI: 10.1186/1471-2407-12-530

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