• DOI:10.1056/NEJMoa1408758
Corpus ID: 205097100

Fractional flow reserve-guided PCI for stable coronary artery disease.

@article{Bruyne2014FractionalFR,
  title={Fractional flow reserve-guided PCI for stable coronary artery disease.},
  author={B. de Bruyne and William F. Fearon and N. Pijls and E. Barbato and Pim A. L. Tonino and Z. Pir{\'o}th and N. Jagic and Sven Mobius-Winckler and G. Rioufol and N. Witt and P. Kala and P. MacCarthy and T. Engstroem and K. Oldroyd and Kreton Mavromatis and G. Manoharan and P. Verlee and O. Frobert and N. Curzen and Jane B. Johnson and A. Limacher and E. N{\"u}esch and P. J{\"u}ni},
  journal={The New England journal of medicine},
  year={2014},
  volume={371 13},
  pages={
          1208-17
        }
}

• B. de Bruyne, William F. Fearon, +20 authors P. Jüni
• Published 2014
• Medicine
• The New England journal of medicine

BACKGROUND We hypothesized that in patients with stable coronary artery disease and stenosis, percutaneous coronary intervention (PCI) performed on the basis of the fractional flow reserve (FFR) would be superior to medical therapy. METHODS In 1220 patients with stable coronary artery disease, we assessed the FFR in all stenoses that were visible on angiography. Patients who had at least one stenosis with an FFR of 0.80 or less were randomly assigned to undergo FFR-guided PCI plus medical… Expand

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