Fractional anisotropy of cerebral white matter and thickness of cortical gray matter across the lifespan

@article{Kochunov2011FractionalAO,
  title={Fractional anisotropy of cerebral white matter and thickness of cortical gray matter across the lifespan},
  author={Peter V. Kochunov and David C. Glahn and Jack L. Lancaster and Paul M. Thompson and V. Kochunov and B. Rogers and Peter T. Fox and John Blangero and D. E. Williamson},
  journal={NeuroImage},
  year={2011},
  volume={58},
  pages={41-49}
}
We examined age trajectories of fractional anisotropy (FA) of cerebral white matter (WM) and thickness of cortical gray matter (GM) in 1031 healthy human subjects (aged 11-90 years). Whole-brain FA and GM thickness values followed quadratic trajectories with age but the relationship between them was linear, indicating that a putative biological mechanism may explain the non-linearity of their age trajectories. Inclusion of the FA values into the quadratic model of the whole-brain and regional… CONTINUE READING

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