Fraction size and the repair of potentially lethal radiation damage in a human melanoma cell line. Possible implications for radiotherapy.

@article{Weichselbaum1982FractionSA,
  title={Fraction size and the repair of potentially lethal radiation damage in a human melanoma cell line. Possible implications for radiotherapy.},
  author={Ralph R. Weichselbaum and Arnold W. Malcolm and J. B. Little},
  journal={Radiology},
  year={1982},
  volume={142 1},
  pages={225-7}
}
Studies performed on a human melanoma line in exponential growth showed radiation survival parameters similar to those of other tumors (n = 1.2, D0 = 151). In plateau-phase cultures, however, this tumor cell line was efficient in the repair of potentially lethal radiation damage, especially when large dose fractions were employed (there was a 48-fold… CONTINUE READING