Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis.

@article{BucklandWright1996FractalSA,
  title={Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis.},
  author={J. Christopher Buckland-Wright and John A. Lynch and Diana G. Macfarlane},
  journal={Annals of the rheumatic diseases},
  year={1996},
  volume={55 10},
  pages={749-55}
}
OBJECTIVE To determine whether fractal signature analysis (FSA) of digitised macroradiographs of knees quantifies alterations in trabecular structure in the tibial cancellous bone of osteoarthritic patients with either early or definite joint space narrowing compared with non-arthritic subjects. METHODS 90 osteoarthritic knees had macroradiographs at x5 magnification. Joint space width and FSA of horizontal and vertical trabecular organisation in the tibial subarticular cancellous bone were… CONTINUE READING