Fractal dynamics in physiology: alterations with disease and aging.

@article{Goldberger2002FractalDI,
  title={Fractal dynamics in physiology: alterations with disease and aging.},
  author={Ary L. Goldberger and Luis A. Nunes Amaral and Jeffrey M. Hausdorff and Plamen Ch. Ivanov and C. K. Peng and Harry Eugene Stanley},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 Suppl 1},
  pages={2466-72}
}
According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary to the predictions of homeostasis, however, the output of a wide variety of systems, such as the normal human heartbeat, fluctuates in a complex manner, even under resting conditions. Scaling techniques adapted from statistical physics reveal the presence of long-range, power-law correlations, as part of multifractal cascades operating… CONTINUE READING
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References

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Showing 1-7 of 7 references

Nonlinear Dynamics, Self-Organization, and Biomedicine, ed

  • Peng, C.-K, J. M. Hausdorff, A. L. Goldberger
  • 2000

Nonlinear Dynamics, Self-Organization, and Biomedicine

  • J. Walleczek
  • 1999

Biomedical Oscillations and Cellular Rhythms: The Molecular Basis of Periodic and Chaotic Behavior

  • A. Goldbeter
  • 1996

Dynamical Disease: Mathematical Analysis of Human Illness (Am

  • J. Belair, L. Glass, U. an der Heiden, J. Milton, eds
  • 1995

Fractal Physiology (Oxford

  • J. B. Bassingthwaighte, L. S. Liebovitch, B. J. West
  • 1994

From Clocks to Chaos: the Rhythms of Life (Princeton Univ. Press, Princeton)

  • L. Glass, M. C. Mackey
  • 1988

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