Fractal dimension as a quantitator of the microvasculature of normal and adenomatous pituitary tissue.

@article{Ieva2007FractalDA,
  title={Fractal dimension as a quantitator of the microvasculature of normal and adenomatous pituitary tissue.},
  author={Antonio Di Ieva and Fabio Grizzi and Giorgia Ceva-Grimaldi and Carlo Russo and Paolo Gaetani and Enrico Aimar and Daniel Levi and Patrizia Pisano and Flavio Tancioni and Giancarlo Nicola and Manfred Tschabitscher and Nicola Dioguardi and Riccardo Rodriguez Y. Baena},
  journal={Journal of anatomy},
  year={2007},
  volume={211 5},
  pages={673-80}
}
It is well known that angiogenesis is a complex process that accompanies neoplastic growth, but pituitary tumours are less vascularized than normal pituitary glands. Several analytical methods aimed at quantifying the vascular system in two-dimensional histological sections have been proposed, with very discordant results. In this study we investigated the non-Euclidean geometrical complexity of the two-dimensional microvasculature of normal pituitary glands and pituitary adenomas by… CONTINUE READING