Foxp3 gene expression in oral lichen planus: a clinicopathological study.

@article{Lei2014Foxp3GE,
  title={Foxp3 gene expression in oral lichen planus: a clinicopathological study.},
  author={Lei Lei and Lihua Zhan and Weixia Tan and Shaohua Chen and Yangqiu Li and M. Reynolds},
  journal={Molecular medicine reports},
  year={2014},
  volume={9 3},
  pages={928-34}
}
CD4+CD25+ Forkhead‑box protein 3 (Foxp3+) regulatory T cells are important in oral lichen planus (OLP). The present study aimed to investigate Foxp3 expression in CD4+CD25+ T cells of peripheral blood mononuclear cells and oral lesions in patients diagnosed with OLP, who were grouped as OLP subtype, duration and relapse. Using quantitative polymerase chain reaction (qPCR), western blotting and immunohistochemistry, Foxp3 expression levels in explants of oral lesions and CD4+CD25+ T cells from… CONTINUE READING
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